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anti drp 1  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc anti drp 1
    Anti Drp 1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+drp+1/pmc12862736-41-11-34
    Average 86 stars, based on 1 article reviews
    anti drp 1 - by Bioz Stars, 2026-09
    86/100 stars

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    other:

    Article Title: Dimethyl fumarate modulates the dystrophic disease program following short-term treatment.
    Article Snippet: Primary antibodies used were anti– DJ-1 and anti–DJ-1 Cys106 (from Craig Goodman, Centre for Muscle Research, University of Melbourne), anti-Desmin (1:1,000; 5332; Cell Signaling Technology [CST]), anti-DJ1 (1:1,000; 5933; CST), anti-Dystrobrevin (1:500; 610766; BD Biosciences), anti-Dystrophin (1:500; ab15277; Abcam), anti–DRP-1 (1:1,000; 8570; CST), anti–HO-1 (1:1,000; ADI-SPA-896; Enzo Life Sciences), anti-KEAP1 (1:1,000; 8047; CST), anti–NF-κB (1:500; 8242; CST), anti–phospho–NF-κB (1:500; 3033; CST), anti-NQO1 (1:1,000; 62262; CST), anti-Nrf2 (1:1,000; 12721; CST), anti–OPA-1 (1:1,000; 80471; CST), anti–phospho-p38 (1:750; 4511; CST), anti-p62 (1:1,000; 5114; CST), anti–phospho-p62 (1:500; 95697; CST), anti–PGC-1α (1:1,000; AB3242; MilliporeSigma), anti-PPARγ (1:1,000; 2492; New England Biolabs), anti–SOD-1 (1:3,000; ADI-SOD-101; Enzo Life Sciences), anti-STAT3 (1:1,000; 12640; CST), anti–phospho-STAT3 (1:2,000; 9145; CST), anti-TFAM (1:1,000; ab252432; Abcam), and total OXPHOS cocktail (1:1,000; ab110413; Abcam).

    Article Title: Dimethyl fumarate modulates the Duchenne muscular dystrophy disease program following short-term treatment in mdx mice
    Article Snippet: Primary antibodies used were: anti-Desmin (1:1000; #5332; CST), anti-DJ1 (1:1000; #5933; CST), anti-Dystrobrevin (1:500; #610766; BD Biosciences), anti-Dystrophi (1:500; ab15277; Abcam), anti-DRP-1 (1:1000; #8570; CST),) anti-HO-1 (1:1000; ADI-SPA-896; Enzo Life Sciences), anti-KEAP1 (1:1000; #8047; CST), anti-NF-κB (1:500; #8242; CST), anti-phospho-NF-κB (1:500; 3033; CST), anti-NQO1 (1:1000; #62262; CST), anti-Nrf2 (1:1000; #12721; CST), anti-OPA-1 (1:1000; #80471; CST), anti-phospho-p38 (1:750; #4511; CST), anti-p62 (1:1000; #5114; CST), anti-phospho-p62 (1:500; #95697; CST), anti-PGC-1α (1:1000; AB3242; Sigma-Aldrich), anti-SOD 1 (1:3000; ADI-SOD-101; Enzo Life Sciences), anti STAT3 (1:1000; #12640; CST), anti-phospho-STAT3 (1:2000; #9145; CST) and anti-TFAM (1:1000; ab252432; Abcam).

    Article Title: Dimethyl fumarate modulates the dystrophic disease program following short-term treatment
    Article Snippet: Primary antibodies used were anti–DJ-1 and anti–DJ-1 Cys 106 (from Craig Goodman, Centre for Muscle Research, University of Melbourne), anti-Desmin (1:1,000; 5332; Cell Signaling Technology [CST]), anti-DJ1 (1:1,000; 5933; CST), anti-Dystrobrevin (1:500; 610766; BD Biosciences), anti-Dystrophin (1:500; ab15277; Abcam), anti–DRP-1 (1:1,000; 8570; CST), anti–HO-1 (1:1,000; ADI-SPA-896; Enzo Life Sciences), anti-KEAP1 (1:1,000; 8047; CST), anti–NF-κB (1:500; 8242; CST), anti–phospho–NF-κB (1:500; 3033; CST), anti-NQO1 (1:1,000; 62262; CST), anti-Nrf2 (1:1,000; 12721; CST), anti–OPA-1 (1:1,000; 80471; CST), anti–phospho-p38 (1:750; 4511; CST), anti-p62 (1:1,000; 5114; CST), anti–phospho-p62 (1:500; 95697; CST), anti–PGC-1α (1:1,000; AB3242; MilliporeSigma), anti-PPARγ (1:1,000; 2492; New England Biolabs), anti–SOD-1 (1:3,000; ADI-SOD-101; Enzo Life Sciences), anti-STAT3 (1:1,000; 12640; CST), anti–phospho-STAT3 (1:2,000; 9145; CST), anti-TFAM (1:1,000; ab252432; Abcam), and total OXPHOS cocktail (1:1,000; ab110413; Abcam).

    Article Title: Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells.
    Article Snippet: High-altitude cerebral edema (HACE) is the severe type of acute mountain sickness, which is still lack of effective therapy.. This study investigated for the first time the protective effect of mitochondrial division inhibitor-1 (mdivi-1) against cerebral edema induced by simulated high-altitude exposure in mice.. It was found that mdivi-1 effectively inhibited phosphorylation of dynamin-related protein-1 (Drp1), reduced expression of AQP4, decreased secretion of IL-6 and TNF-α, and alleviated cerebral edema in mice.

    Article Title: Resveratrol Mitigates Uremic Toxin-Induced Intestinal Barrier Dysfunction in Chronic Kidney Disease by Promoting Mitophagy and Inhibiting Apoptosis Pathways
    Article Snippet: Primary antibodies as follows: Anti-ZO-1(Cell Signaling Technology, Danvers, MA, USA), anti-Occludin (Cell Signaling Technology, Danvers, MA, USA), anti-Occludin-1 (Cell Signaling Technology, Danvers, MA, USA), anti-Occludin-2 (Cell Signaling Technology, Danvers, MA, USA), anti-IRF-1 (GeneTex, Hsinchu City, Taiwan), anti-DRP-1 (Cell Signaling Technology, Danvers, MA, USA), anti-Ho-1(Cell Signaling Technology, Danvers, MA, USA), anti-Bax (Cell Signaling Technology, Danvers, MA, USA), anti-Bcl-2 (Cell Signaling Technology, Danvers, MA, USA), anti-cytochrome C (Abcam, Cambridge, UK), anti-caspase 3 (Cell Signaling Technology, Danvers, MA, USA), anti-PARP-1 (Cell Signaling Technology, Danvers, MA, USA), anti-LC3 A/B (Cell Signaling Technology, Danvers, MA, USA), anti-P62 (Cell Signaling Technology, Danvers, MA, USA), anti-mTOR (Cell Signaling Technology, Danvers, MA, USA) and anti-PI3K/AKT (Cell Signaling Technology, Danvers, MA, USA), and anti-β Actin (Proteintech, Rosemont, IL, USA).

    Article Title: Timing of Glucocorticoid Treatment Dictates Glucocorticoid Receptor Actions Modulating the NLRP3‐Inflammasome Activation in Macrophages
    Article Snippet: Human and mouse anti‐GR (RRID:AB_11179215), anti‐IRG1/ACOD1 (RRID:AB_3064865), anti‐iNOS (RRID:AB_2687529), anti‐NLRP3 (RRID:AB_2722591), anti‐DRP‐1 (RRID:AB_10950498), anti‐MFN‐2 (RRID:AB_2716838), anti‐pro‐IL‐1β (RRID:AB_2721117), anti‐Caspase‐1 (RRID:AB_2890194), anti‐GSDM‐D (RRID:AB_2916333), anti‐cleaved IL‐1β (RRID:AB_2799639), anti‐NRF2 (RRID:AB_2715528), anti‐HIF‐1α (RRID:AB_2622225), and anti‐DUSP1/MKP1 (RRID:AB_3371713) were purchased from Cell Signaling Technology (Danvers, MA, USA).

    Bioprocessing:

    Article Title: Bok regulates mitochondrial fusion and morphology.
    Article Snippet: Antibodies raised in rabbits were: anti-IP3R1 and anti-IP3R2 [35], anti-erlin2 [37], anti-IP3R1–3 [38], anti-Mcl-1 #D35A5, anti-Bcl-xL #54H6, anti-Bcl-2 #50E3, anti-caspase-3 #9662, anti-PARP #9542, anti-Mfn2 #9482, anti-VDAC1 #4661, and antipDrp1-616 #3455 (Cell Signaling Technology), anti-Bak #06-536 (Millipore), anti-Bax #N-20 and anti-Tom20 #FL145 (Santa Cruz Biotechnology Inc.), anti-Bok, raised against amino acids 19–32 of mouse Bok [4, 7], and antiMiro1 #HPA010687 (Atlas Antibodies). .. Mouse monoclonal antibodies were: anti-FLAG epitope clone M2 (Sigma), anti-IP3R3, raised against amino acids 22–230 of human IP3R3 (BD Transduction Labs), anti-Mfn1 #D-10 (Santa Cruz Biotechnology Inc.), anti-Drp-1 #14647 (Cell Signaling Technology), anti-electron transport chain complexes #110413 (Abcam), and anti-p97 (Research Diagnostics Inc.). .. Horseradish peroxidase-conjugated secondary antibodies, gonadotropin-releasing hormone (GnRH), oleoyl-L-α-lysophosphatidic acid (LPA), protease inhibitors, Triton X-100, 3-[(3-cholamidopropyl)-dimethylammonio]1-propanesulfonate (CHAPS), brefeldin A (BFA), tunicamycin (TN), and thapsigargin (TG) were purchased from Sigma.

    Article Title: Bok regulates mitochondrial fusion and morphology
    Article Snippet: Antibodies raised in rabbits were: anti-IP 3 R1 and anti-IP 3 R2 [ 35 ], anti-erlin2 [ 37 ], anti-IP 3 R1–3 [ 38 ], anti-Mcl-1 #D35A5, anti-Bcl-xL #54H6, anti-Bcl-2 #50E3, anti-caspase-3 #9662, anti-PARP #9542, anti-Mfn2 #9482, anti-VDAC1 #4661, and anti-pDrp1-616 #3455 (Cell Signaling Technology), anti-Bak #06-536 (Millipore), anti-Bax #N-20 and anti-Tom20 #FL145 (Santa Cruz Biotechnology Inc.), anti-Bok, raised against amino acids 19–32 of mouse Bok [ 4 , 7 ], and anti-Miro1 #HPA010687 (Atlas Antibodies). .. Mouse monoclonal antibodies were: anti-FLAG epitope clone M2 (Sigma), anti-IP 3 R3, raised against amino acids 22–230 of human IP 3 R3 (BD Transduction Labs), anti-Mfn1 #D-10 (Santa Cruz Biotechnology Inc.), anti-Drp-1 #14647 (Cell Signaling Technology), anti-electron transport chain complexes #110413 (Abcam), and anti-p97 (Research Diagnostics Inc.). .. Horseradish peroxidase-conjugated secondary antibodies, gonadotropin-releasing hormone (GnRH), oleoyl- l -α-lysophosphatidic acid (LPA), protease inhibitors, Triton X-100, 3-[(3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate (CHAPS), brefeldin A (BFA), tunicamycin (TN), and thapsigargin (TG) were purchased from Sigma.



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    Image Search Results


    The results of western blotting (A) . The protein levels of PGC-1α (B) and Drp-1 (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.

    Journal: PLOS One

    Article Title: Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study

    doi: 10.1371/journal.pone.0336221

    Figure Lengend Snippet: The results of western blotting (A) . The protein levels of PGC-1α (B) and Drp-1 (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.

    Article Snippet: Monoclonal antibodies were against PGC-1α (ab54481, Abcam), NF-κB p65 (ab16502, Abcam), Drp-1 (sc-271583), ATF3 (sc-518032), p-p53 (sc-377553), p-p21 (sc-377569), and caspase-3 (sc-7272) (Santa Cruz Biotechnology, Inc).

    Techniques: Western Blot, Control